aeruginosa acquisition were history of previous P. Individual characteristics significantly associated with P. aeruginosa on admission, 201 (15%) acquired P. Hazard ratios (HRs) were estimated using multivariate Cox model.Īmong the 1314 patients without P. aeruginosa water and patient colonization pressures, and ICU characteristics were collected. Data on patient characteristics, invasive devices exposure, antimicrobial therapy, P. Water samples were obtained weekly on water taps of the ICUs. aeruginosa acquisition was defined by a subsequent colonization or infection if screening swabs on admission were negative. aeruginosa colonization on admission, weekly and before discharge. Adult patients hospitalized in ICU for ≥ 24 h were included and screened for P. aeruginosa acquisition.Ī five-month prospective multicentric study was performed in ten French ICUs. To identify individual and environmental ICU risk factors for P. Pseudomonas aeruginosa is a major nosocomial pathogen in intensive care units (ICUs) however, endogenous versus exogenous origin of contamination remains unclear. 17 CHU, Unité de soutien méthodologique à la recherche clinique et épidémiologique, Bordeaux, France INSERM, U897 Epidemiologie et Biostatistique, Bordeaux, France Univ Bordeaux, ISPED, Bordeaux, France.16 INSERM U657, Université de Bordeaux, Bordeaux, France CHU, Hygiène hospitalière, Bordeaux, France.15 CHU, Unité de soutien méthodologique à la recherche clinique et épidémiologique, Bordeaux, France.14 CHU, Laboratoire de bactériologie, Bordeaux, France UMR 5234 CNRS, Université de Bordeaux, Bordeaux, France.13 CHU, Réanimation médicale, Bordeaux, France.12 CH Lens, Hygiène hospitalière, Lens, France.Herriot, Laboratoire d'hygiène, Lyon, France. 10 CHU Lyon Sud, Réanimation médicale, Lyon, France.9 CHU Poincaré, AP-HP, Réanimation médicale, Garches, France.8 CHU Poincaré, AP-HP, Hygiène hospitalière, Garches, France.7 CHU Lariboisière, AP-HP, Réanimation médicale, Paris, France.

6 CHU Lariboisière, AP-HP, Hygiène hospitalière, Paris, France.5 CH DRon, Réanimation et maladies infectieuses, Tourcoing, France.4 CHU, Hygiène hospitalière, Montpellier, France.3 CHU, Hygiène hospitalière, Besançon, France.Electronic address: 2 CHU, Hygiène hospitalière, Bordeaux, France. 1 CHU, CCLIN Sud-Ouest, Bordeaux, France INSERM U657, Université de Bordeaux, Bordeaux, France.

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